【摘要】 本文对43种蛋白质的肽链进行了统计分析,计算了相邻三个氨基酸的构象参数R_α、R_β、R_c,并将其分类;在此基础上提出了氨基酸的突变对蛋白质二级结构影响的规律。研究了细胞色素C可变氨基酸的突变(不同种属之间)、血红蛋白(人)的异常。给出了所有可能的中间氨基酸可突变为半胱氨酸的氨基酸三联体。更多还原

【Abstract】 In this paper, the statistical analysis of peptide bonds of 43 proteins is given, the conformational parameters R, R, and R of three neighbour amino acids are calculated and classified.On this base, the law of the effect of amino acids’ mutable amino acid; of cytochrome C (between different species) the abnormal hemoglobin (human) is studied. All possible amino acids triplets are proposed,in which the middle one is able to mutate to cystine.更多还原