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体外比较三个人肺腺癌细胞系的侵袭特性

Comparison of Invasiveness of Three Human Lung Adenocarcinoma Cell Lines in Vitro

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【作者】 何滨; 时德志; 班翔; 郝宵明;

【Author】 He Bin et al(Department of Pathology)

【机构】 哈尔滨医科大学病理学教研室; 哈尔滨医科大学病理学教研室;

【摘要】 在器官培养中发现,3个不同来源的低分化人肺腺癌细胞系(LTEP-a2、Anip、LGC-7910)在侵袭人的心、肝脏器官时表现了不同的生物学特性,包括侵袭形式、侵袭速度、变形能力和对靶器官破坏程度以及细胞的分裂繁殖等方面。本实验对其进行了较详细的观察。

【Abstract】 In organ culture, it was found that there were some differences in invasiveness to human heart and liver fragments among three lines of human lung adenoc- arcinoma cells. The differences could be found in the morphological pattern, speed of invasion, the deformability of tumor cells, number of mitosis, as well as the destruction of the target organ. The results suggest that the invasiveness of the tumors is influenced not only by tissue properties but also by tumor cells themself, and tumor cells with similar degree of differentiation in morphology can show apparently different biological behaviour.

【关键词】 肿瘤; 器官培养; 肺腺癌; 侵袭特性;
【Key words】 Organ culture; Human lung adenocarcinoma; Invasiveness;
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1988年05期
  • 【被引频次】1
  • 【下载频次】18
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