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用Ames点试验法对日用化工品致突变性的研究(附30种分析报告)

STUDY OF THE MUTAGENICITY OF DAILY USED CHEMINCALS WITH AMES’SPOT TEST (ANALYSIS OF 30 KINDS)

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【作者】 张蔓蔓王敬之王美华

【Author】 Zhang Manman Wang Jingzhi Wang Meihua Department of Microbiology

【机构】 河北医学院微生物学教研室河北医学院微生物学教研室

【摘要】 本文对30种日用化工品进行了Ames′试验研究。结果表明:洗衣粉、洗发膏有致突变作用,染发剂和治疗性化妆品大部分有致突变作用;一些护肤营养类化妆品则无。实验中发现的大部分致突变物质在高浓度时有抑制环,诱变作用不明显,经稀释到合适浓度后才有明显的致突变作用。

【Abstract】 In this study, 30 kinds of chemicals used daily have been examined by Ames′spot test. These results demonstrated that detergents. including washing powder and shampoos, have the mutagenicity. Most of the hair colorants and therapeutic consmetics have also the mutagenicity. All of the venishing cream used for keeping in good repair of the skin have no mutagenic effect on the bacteria. Most of the mutagens found in this study reyeal the inhibitory effect on the growth of the bacteria in high concentration but the mutagenicity is not obvious. However, if the mutagen is diluted to appropriate concentration, the mutagenicity may appear again.

【关键词】 AMes’试验诱变性日用化工品
【Key words】 Ames’ testmutagenicitychemical used daily
  • 【文献出处】 河北医学院学报 , 编辑部邮箱 ,1988年02期
  • 【被引频次】2
  • 【下载频次】32
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