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纤维结合蛋白在流行性出血热病人中的变化

DETERMINATION OF PLASMA FIBRONECTIN IN PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER

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【作者】 蒋延东; 翁维权; 张春源;

【Author】 Jiang Yandong, et al Department of Medicine

【机构】 青岛医学院附院内科; 青岛医学院附院内科;

【摘要】 采用单向免疫扩散法测定104例流行性出血热患者血浆纤维结合蛋白。结果表明,患者血浆纤维结合蛋白水平自发热期开始降低,低血压休克期和少尿期降至最低点,多尿期高于正常水平,恢复早期达最高峰,发病60病日恢复正常。中、重型患者降低较显著;重型患者恢复正常水平所需时间较其它两型为长。

【Abstract】 The plasma fibronectin (FN) concentration in 104 patients withepidemic hemorrhagic fever (EHF) was determined by radioimmuno-dif-fusion. The result showed that plasma FN level dropped down in thefebrile stage and got to the lowest point in the hypotensive and uro-penia stages,and then rapidly rose in the polyuria stage, reaching itspeak in the early convalescent stage. From then on it fell graduallyand came to normal on the 60th day. It was also found that plasmaFN level off the moderate and the severe types in the febrile stagedropped more apparently than that of the mild type,and that the pla-sma FN level of the severe type came to normal the latest.

【关键词】 出血热; 流行性; 载体蛋白类;
【Key words】 Hemorrhagic fever, epidemic; Carrier proteins;
  • 【文献出处】 青岛医学院学报 , 编辑部邮箱 ,1988年04期
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