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银耳多糖、银耳孢子多糖及黑木耳多糖的抗溃疡作用

ANTIULCER EFFECT OF THE POLYSACCHARIDES FROM TREMELLA FUCIFORMIS SPORES OF TREMELLA FUCIFORMIS AND AURICULARIA AURICULA

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【作者】 薛惟建王淑如陈琼华

【Author】 Xue Weijian, Wan Shuru and Chen Qionghua (Division of Biochemistry)

【机构】 中国药科大学生物化学研究室中国药科大学生物化学研究室

【摘要】 银耳多糖、银耳孢子多糖及黑木耳多糖以每天70mg/kg灌胃2d,均明显抑制大鼠应激型溃疡的形成;以每天165mg/kg灌胃124,能促进醋酸型胃溃疡的愈合。对胃酸分泌和胃蛋白酶活性无明显影响。本研究表明,这三种多糖均有抗溃疡作用。

【Abstract】 Three polysaccharides, isolated from Tremella fuciformis Berk, spore of Tremella fuciformis Berk and Auricularia auricula, were found to have inhibition effect on experimental ulcer in rats. The degrees of ulcer induced by stress-restraint were (po 70mg/kg×2d) 1.66, 1.50 and 1.16, compared with 4.33 of control. Areas of ulcer induced by acetic acid were (po 165 mg/kg×12d) 10.69, 9.62 and 11.57mm~2, compared with 19.95mm~2 of control. But the polysaccharides showed ineffectiveness on the secretion of gastric acid and pepsin activity. The results indicate that the polysaccharides possess antiuleer action.

  • 【文献出处】 中国药科大学学报 ,Journal of China Pharmaceutical University , 编辑部邮箱 ,1987年01期
  • 【被引频次】72
  • 【下载频次】335
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