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亚硒酸钠对软骨细胞的保护作用

STUDIES OF PROTECTIVE ACTION OF SODIUM SELENITE ON CHONDROCYTE

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【摘要】 <正> 以硫酸铊致鸡胚软骨细胞坏死做为软骨细胞坏死模型,曾初步探讨了亚硒酸钠拮抗硫酸铊保护软骨细胞的作用。本实验做进一步观察和证实,并通过电镜观察探讨其机制。

【Abstract】 Thallium sulfate may inducechondrodystrophy in chick embr-yo.Ultrastructure changes of th-ese cells showed accumulation inlarge amount of the product ofcell itself.The changes was dueto defect in membrane formationwhich had been induced by thalliumsulfate.With the aid of the gluta-thione peroxidase containing ele-ment selenium,accumulation ofperoxides was prevented,membranesystem was stabilized,and membra-ne defect was improved.Therebychondrocytes were safeguarded.

  • 【文献出处】 中国地方病学杂志 ,Chinese Journal of Endemiology , 编辑部邮箱 ,1987年01期
  • 【被引频次】15
  • 【下载频次】37
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