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酸枣仁化学成分研究Ⅱ

STUDIES ON THE CONSTITUENTS OF ZIZYPHUS SPINOSUS HU

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【作者】 曾路张如意王序

【Author】 ZENG Lu, ZHANG Ru-Yi and WANG Xu (College of pharmacy, Beijing Medical University, Beijing)

【机构】 北京医科大学药学院北京医科大学药学院

【摘要】 自酸枣仁(Zizyphus spinosus Hu)种子的甲醇提取部位(F3)中分离出六个化合物,三个为中性皂甙,酸枣仁皂甙B(Ⅵ),酸枣仁皂甙A(Ⅶ),皂甙Ⅺ(结构待定);一个酚性化合物,阿魏酸(Ⅷ),二个黄酮,spinosin(Ⅸ)和zivulgarin(Ⅹ),其中阿魏酸为首次从酸枣仁中得到,zivulgarin为一新的黄酮类化合物。

【Abstract】 Suan Zao Ren (the seeds of Zizyphus spinosus Hu) is a commonly used in Chinese traditional medicine for treating insomnia, neurasthenia and sometimes for sleepiness caused by physical emaciation. From its methanol fraction, six compounds were isolated. Four of them were identified as triterpenoid saponins, jujuboside B(Ⅵ), jujuboside A (Ⅶ): phenolic acid, ferulic acid (Ⅷ) and flavonoid compound, spinosin (Ⅸ).One flavonoid (compound Ⅹ ) was proved to be a 4″-β-D-glucopyranosyl swertisin, a new flavonoid compound named zivulgarin. The structure of zivulgarin was elucidated by acid hydrolysis, derivative preparation and spectroscopic examination. The remaining saponin (Ⅺ) is being further studied

  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1987年02期
  • 【被引频次】88
  • 【下载频次】825
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