【摘要】 <正> 近年来,国内外对婴幼儿乙型肝炎病毒(HBV)感染的研究极为重视,不少报导认为多数人均已在生命初期受到 HBV 感染,而且婴幼儿 HBsAg 阳性血症与母亲 HBsAg 阳性有密切相关。我们于1981—1983年对 HBsAg 阳性32名和 HBsAg 阴性32名的母亲及其所生婴幼儿的 HBV 感染及影响因素,进行了前瞻性研更多还原

【Abstract】 Thirty two newborns and infants whose mothers were positive for HBsAg and another 32 whose mothers were HBsAg-negative bad been followed up for 2 years.The HBsAg-positive rates were 65.6% and 3.1% respectively.The rates of HBV infection were 75.0% and 3.1% respectively.Of 21 HBsAg-positive children,17 (80.9%)became chronic carriers.In those whose mothers were positive and negative for HBeAg,the HBsAg- positive rates were 52.3% and 57.1% respectively.It suggests that the transmission from mother to newborn is one of the maintransmission routes of HBV.In China,high endemic areas and high HBsAg prevalence rate of hepatitis B may be due mainly to chronic HBsAg carrier state in infants.The key factor ot HBV infection in newborns and infants is their mother’s HBeAg positivity,thus preventive measures should be taken against it.更多还原