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用低分化鼻咽癌细胞株(CNE2)为靶细胞测定鼻咽癌(NPC)患者ADCC作用

The Antibody-Dependent Cell-Mediated Cytotoxicity against NPC Cell Line (CNE2) in NPC Patients

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【作者】 刘庆伦; 蔡体育; 陈爱珍;

【Author】 Liu Qinglun Cai Tiyu Chen Aizhen (Cancer Research Institute)

【机构】 中山医科大学肿瘤研究所免疫室; 中山医科大学肿瘤研究所免疫室;

【摘要】 <正> 抗体依赖的细胞介导的细胞毒(AntibodyDependent Cell-Mediated Cytotoxicity,ADCC.)是机体细胞免疫与体液免疫两大系统的协调作用,在机体的肿瘤免疫、移植免疫,某些真菌,病毒,寄生虫疾患及某些自身免疫疾患的过程中,均发挥重要作用。ADCC对那些吞噬细胞无法吞噬的体积较大的实体瘤、寄

【Abstract】 The ADCC activities of human lymphocytes sgainst poordifferentiated nasopharyngeal carcinoma cell line (CNE2) were studied by using a quantitative 61Cr release assay. The cytotoxicity (CT) was 36.11±12.13%in healthy donors, while it was 35.57±9.39% in NPC patients. There was no significant difference between healthy donors and NPC patients, nor between man and woman.The factors affecting the quantitative 61Cr releas assay were studied. It was shown that this assy is reproducible and practicable.

  • 【文献出处】 中山医科大学学报 , 编辑部邮箱 ,1986年03期
  • 【被引频次】1
  • 【下载频次】23
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