【摘要】 本文用电镜观察实验性心力衰竭时心肌组织的超微结构改变,分析了心功能代偿与失代偿阶段病理形态的差异,认为心功能状态与心肌受损的程度和范围有关。更多还原

【Abstract】 The myocardium of 20 chronic heart fa(?)ure (CHF) rabbits caused by adriamycin was studied by electron microscopy. The main morphological alterations of CHF heart were as follows: changes in biological membrane, including seperation of intercalated disks, degeneration of mitochondria, dilatation of sarcoplasmic reticulum; atrophy, disruption and lysis of myofibrils; edema of cardiomycytes and interstitial fibrosis.Compensated and decompensated CHF were classified according to the general manifestations of the rabbits. The main morphologic differences of myocardium between them were that in the former, the lesions were focal and mitochondriosis was appeared, in the later, the lesions were more diffuse and severe. A close relationship bettween morphologic alterations and heart function was observed.更多还原