【摘要】 <正> 近年来,国内外对婴幼儿乙型肝炎病毒(HBV)感染的研究极为重视,不少报导认为多数人均已在生命初期受到HBV感染,而且婴幼儿HBsAg阳性血症与母亲HBsAg阳性有密切相关。我们于1981—1983年对HBsAg阳性32名和HBsAg阴性32名的母亲及其所生婴幼儿的HBV感染及影响因素,进行了前瞻性研究。对象与方法一、对象更多还原

【Abstract】 Thirty two newborns and mfants whose mothers were positive for HBsAg and another 32 whose mothers were HBsAg-negative had been followed up for 2 years. The HBsAg-positive rates were 65.6% and 3.1% respectively. The rates of HBV infection were 75.0% and 3.1% respectively. Of 21 HBsAg-positive children, 17 (80.9%) became chronic arriers. In those whose mothers were positive and negative for HBeAg, the HBsAgpositive rates were 92.3% and 57.1% respectively. It suggests that the transmission from mother to newborn is one of the maintransmission routes of HBV. In China, high endemic areas and high HBsAg prevalence rate of hepatitis B may be due mainly to chronic HBsAg carrier state in infants. The key factor ot HBV mfection in newborns and infants is their mother’s HBeAg positivity, thus preventive measures should be taken against it.更多还原