【摘要】 <正> 滨海地区居民因长期大量食用高碘海产品或饮用含碘量高的水而发生的高碘地方性甲状腺肿(简称高碘地甲肿)称为海滨地方性甲状腺肿(Endemic Coast Goiter),已先后于日本北海道、我国河北省黄骅县、山东省日照更多还原

【Abstract】 Epidemiological survey and thy-roid function tests were carriedout for endemic goiter prevalent inlow-lying land with saline-alkalinesoil in Xiaoyi County,Shanxi Pro-vince.Middle school students andprimary school pupils were exami-ned.Eleven brigades in the endemicregion got drinking water from sh-allow wells.Analysis of the drink-ing water revealed high level ofiodine,averagely 533.83μg/l;thatof calcium,magnesium,manganese,molybdenum,fluorine were signifi-cantly elevated too.Mean urinaryiodine was 2428.5μg/g of creatini- ne;palpable goiter rate,32.54%;visible goiter rate,11.40%.The re-sults of thyroid function tests we-re:Perchlorate discharge test,positive in 56.52% of 23 patients;serum TSH,elevated;serum totalT₃,T₄,normal;serum TGAb,notelevated and RAIU,normal。It is thought that the high iod-ine level in water is the main ca-use of endemic goiter in that reg-ion and high concentrations of theother elements may play a partin the pathogenesis.The reasonwhy iodide goiter are endemicallyprevalent in the inland far fromseacoast is discussed.It is suggestedthat the possibility of iodide goitershould be ruled out in those ende-mic goiters occurring in low-lyingland with saline-alkaline soil.Wepropose endemic goiter should beclassified into two categories,hy-poiodic and hyperiodic,the laterbeing further divided into seacoa-st type and inland type.更多还原