【摘要】 <正> 地方性甲状腺肿多由缺碘所致。但近年来根据流行病学调查及动物实验分析,摄入过量碘亦可以引起甲状腺肿,即高碘甲状腺肿。所谓高碘性甲状腺肿是指由于服用或随饮食摄入的碘量,超过人体生理需要之后所形成的甲状腺肿。1965年 Suzuki 报道了日本北海更多还原

【Abstract】 Experimental goiter was occuringin mice fed with excess iodide(potassium iodide).When the iod-ide contained in feedings was increased gradually,the thyroid wei-ghts and the diameters of follicleswere significantly increased,butthe height of thyroid cells wasmarkedly decreased.The follicle lumina of the iodi-de goiter were fully filled with co-lloid,and the electronic density infollicle lumina was moderate.Theother changes in the experimentalgoiter was that the epithelial cellsof follicles changed into flated,the nuclei of cells deformed,thegranular endoplasmic reticula enl-arged,mitochondria swelled andthe number of lysosome increased,but no significant changes of thyr-oid function were found.更多还原