节点文献

33对习惯性流产夫妇的染色体研究

HABITUAL ABORTION AND CHROMOSOME ABNORMALITIES——Report of 33 couples

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【摘要】 <正> 习惯性流产(Habitual abortion)是妇产科中较为常见的疾病,它是指3次或3次以上的连续自发流产,现在许多研究也把2次连续自发流产包括在内。本病发病原因与很多因素有关,如生殖器官异常、内分泌紊乱、免疫因素、感染以及遗传因素等。多年来细胞遗传研究表明染色体异常是引起习惯性流产的主要原因之一。

【Abstract】 In this report, thirty three couples who had two or more consecutive abor tions were studied, and five chromo some abnormalities were found. The abnormal karyotypes were 46, XX, t(4; 6) (q35; q21) , 46, XX, t(2; 3)(q33; p25 ) , 46, XX, inv (7) (q22 q36) , 46, XX, 15p~+, 46,XX/47, XXX (1/152).It was shown that the chromosome abnormalities were the important cause of the habitual abortions. The average incidence of chromosome aberration is 4.90% in the literatures and 7.58% in this report.Balanced chromosomal transloca tions are frequent found in couples who had habitual abortions. The average incidence is 3.89% in literature and 3.03% in this report. Besides translo cations, there are some other chromo some aberrations, such as inversion, sex chromosome abnormality and so on.There are more chromosome abnor malities in wives than in husbands, in this report all chromosome abnorma lities were found in wives.

  • 【文献出处】 遗传与疾病 , 编辑部邮箱 ,1985年01期
  • 【被引频次】3
  • 【下载频次】11
节点文献中: