【摘要】 <正> 在我国,对血红蛋白病的临床、发生率、遗传与一级结构分析等方面都已进行了较系统的研究。据已有资料,发现的异常血红蛋白多无临床表现,仅当其合并地中海贫血时才有贫血。随着社会医学的发展,应该在我国找出具有临床表现的血红蛋白病的高发人群,并在高发区系统开展临床治疗、预防性的更多还原

【Abstract】 The incidences of abnormal hemo globin and thalassemia were surveyed in south-west Yunnan Province among a population of 4420. One hundred and eighty nine cases of abnormal hemoglo bin were found with an incidence of 4.28%. The incidences of α-thalassemia and β-thalassemia were 0.05% and 10.95% respectively. It showed that south-west Yunnan had the highest incidence of hemoglobinopathies in China.Among the variants of hemoglo binopathies found in these districts, HbE was the commonest one (97.8%). There were 168 cases of heterozygous HbE, 9 cases of homozygous HbE,and 8 cases of HbE-β-thalassemia.The incidences of abnormal hemo globin were higher and higher from north-east to south-west in the surveyed districts. The incidences of Dali, Chuxiong, Baoshan and Dehong were 0.49%, 1.49%, 3.97% and 11.2% respectively. Among nine nationalities surveyed abmormal hemoglobins were found in seven of them.They were Jingpo (5/36) , Dai (11.76%) , Lisu (10.44%) , Benglong (5.30%) , Yi (1.78%),Hand. 16%)and Bai(0.48%). The incidences of all these nationalities were higher than that of the adjusted incidence surveyed in 14 provences and autonomous regions.更多还原