【摘要】 本文用光学活性2-氨基丁醇-1（3）作拆分剂,对（±）-磷酸一氢-1,1＇-联-2,2＇-萘酯（2）进行拆分。用（+）-3或（-）-3中的任一种化合物作为拆分剂,都能在乙醇-乙酸乙酯混合溶剂中通过分步结晶法,一次拆分得到两个高旋光纯度的2对映异构体,拆分得率分別为68%和51%。光活性2经LiAIH₄还原可得高产率（97%）的光活性1,1＇-联-2-萘酚,构型不变。更多还原

【Abstract】 A convenient method of resolution of 1,1′-bi-2,2′-naphthyl hydrogenphosphate(2),synthesized from β-naphthol,with(+)-or(-)-2-aminobutanol-1(3) as resolving agent is reported.Both enantiomers of 2 with high optical purity can be su-ccessfully obtained as crystalline salt of either(+)-or(-)-3 in a mixed solvent ofethanol/ethyl acetate.Optical active 1 is obtained by reduction of corresponding 2 withlithium aluminium hydride in excellent yield without inversion of the configuration.更多还原