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乙型肝炎核心抗体在正常人群中的分布及其传染源作用

Distribution of Anti-HBc in Normal Population and Its Effect as A Source of Infection

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【作者】 范殿英; 于素芳; 韩风文; 叶秀文; 赵学江;

【Author】 Fan Dianying,Tianjin Hygiene and Prevention Disease Centre

【机构】 天津市卫生防病中心肝炎研究室; 天津市卫生防病中心肝炎研究室;

【摘要】 <正> 乙型肝炎核心抗原及其抗体,在乙型肝炎感染上作用很大,因核心抗原不易在血清中检出,因此血清中抗-HBc 的检测即做为乙肝诊断和传染性大小的重要指标。抗-HBc 在血清中用敏感方法检测阳性率很高,不同类型的抗-HBc 出现有何意义,是一个值得研究探讨的问题。为此目的,我们应用美国 Abbott 公司的 ELISA 试剂盒,对

【Abstract】 Sera of 348 healty adults were collect to detect Anti-HBc by ELISA (AbbottUSA).The positive rate Anti-HBc was 51.2%.The positive rate rises as the ageincreases.The highest positive rate is between age 41~50 years which is 79.2%.Amongdifferent groups of professions the highest percentage is in the medical service whichis 80.8%.There were seven types of Anti-HBc detected in the sera.The most commontype is Anti-HBc together with Anti-HBs existed at the same time in the serawhich is 53.4%.Sera containing Anti-HBc alone are 27.5%.Anti-HBc blood haven’ttransfusion of cause hepatitis.But transfusion of blood containing both HBsAg and Anti-HBc,hepatitis occur-red.Mothers containg Anti-HBc alone in their sera haven’t been found HBsAg in thesera of their 3 children.So,The authors concluded that sera containing Anti-HBcalone is much less infectious than sera containing both Anti-HBc and HBsAg.

  • 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1985年06期
  • 【被引频次】4
  • 【下载频次】42
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