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分期结扎兔颈总动脉和椎动脉对血压、心率、心电图和基底动脉的影响
The Effect on Blood Pressure, Pulse Rate, Electrocardiogram and Basilar Artery of Bilateral Carotid and Vertebral Arteries Ligation in the Rabbit at Successive Intervals
【摘要】 <正> 当脑部患有肿瘤、血管瘤和血管出血等疾病时,结扎颈部血管以缓解症状是必需的,但颈总动脉和椎动脉结扎后产生脑贫血,将对心血管系统带来何种影响,这是一个值得探讨的问题。关于对血压和心率的影响曾有过一些研究,而对心电图和基底动脉的影响未见报道。本实验的目的是分三次结扎兔的双侧颈总动脉和椎动脉,欢察动物的血压、心率、心电图和基底动脉的变化,以便提供一些实验动物的资料为临床参考。
【Abstract】 Twenty-three rabbits of both sexes are studied, arranged in weight from 2.1 to 3kg. They are divided into experimental and controled groupsBlood pressure, pules rate electrocardiogram(ECG) of all animals measured, and changes of basilar artery are observed. The results obtained are as follows.(1) Blood pressure and pulse rate in the experimetal animals are shown in Figure 1. After bilateral carotid and vertebral ligation, pulse rate increases and blood pressure rises. But no rabbit shows persistent hypertension.(2) The huge and tall T wave and the raised ST segment in ECG are seen. The altitude of T wave in experimental animals are higher than that of controled animals. The difference between the two is significant (p<0.01).(3) After deganglionate cervical superioe the basilar artery was not enlarged. It was enlarged in bilateral carotid ligation or bilateral carotid ligation. However, ligation of the bilateral carotid and unilateral vertebral produced three flexures in the basilar artery, while bilateral carotid and verterbral ligation produced four flexures(Figure 2.Table 1)。
- 【文献出处】 南昌大学学报(理科版) ,Journal of Nanchang University(Natural Science) , 编辑部邮箱 ,1985年01期
- 【被引频次】1
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