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用苹果Ⅱ型微机实时分析在位心肌细胞跨膜电位的初步研究

PRELIMINARY STUDY ON ANALYSING TRANSMEMBRANE ACTION POTENTIAL OF CARDIAC MUSCLE CELL BY USING APPLE—ⅡMICROCOMPUTER

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【作者】 曾晓荣; 朱寄天; 冯志强; 刘晓川; 张玉; 金敏; 杨清建;

【Author】 Zeng Xiaorong,et al Department of Myocardium Electrophysiology Jin Min,et al Department of Physics,Zhejiang Univ

【机构】 泸州医学院心肌电生理学研究室; 泸州医学院心肌电生理学研究室; 浙江大学物理系;

【摘要】 作者使用苹果Ⅱ型微机对蛙、大鼠、家兔、山羊、犬、牛在位心肌细胞及培养乳鼠心肌细胞的跨膜电位进行了实时分析。测量了RP、OS、APA,Vmax及其相应的膜电位、APD10、APD50、APD80以及二相、三相斜率等参数,达到了自动测量、实时分析、图表显示、操作简便、结果较为准确,为传统的电生理实验提供了先进的研究方法和手段。

【Abstract】 Apple-Ⅱ microcomputer was used for experiments in cardiac electrophysiology. The experiments of cardiac muscle cell transmembrane potential in situ were analysed by the microcomputer. They contained: automatic measuring resting potential, over shoot, action potential duration, action potential high, analysing the maximum rate of rise of the action potential, and slope 2, slope 3. The results showed that the measurement by microcomputer is more ac-curate and takes less time compared with traditional method, therefore, the new method may provide a better means for cardiac electrophysiological experiment.

  • 【文献出处】 泸州医学院学报 ,Journal of Luzhou Medical College , 编辑部邮箱 ,1985年04期
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