【摘要】 <正> 人类各种疾病中血清总补体或单一成分含量可发生变化,因之补体水平测定或组织定位观察有助于对某些疾病发病机理的探讨。有关实验证实在实验性矽肺动物模型大鼠肺巨噬细胞表面 C₃受体增加并有促进吞噬功能的现象,且测定矽肺和煤矽肺病人外周血中补体 C₃含量有显著增高,但也有报导矽肺和煤矽肺病人血清补体 C₃水平变化不显或甚致下降。为此我们使用二种更多还原

【Abstract】 Sera taken from patients with anthrasilicosis or asbestosis,from patients in whom the diag- nosis pneumoconiosis was not comfirmed (doubtful),and from exposed workers,was tested for C3 concentration using two different methods.A eomparision between the two tests indicated that the rocket electrophoresis test is more sensitiv than the radial immunodiffusion test. The results showed that the serum C3 level in patients with stage Ⅱ anthrasilicosis,stage Ⅰ anthrasilicosis and no comfirmed diagnosis,as well as in workers exposed to coal dusts,was not significantly different from that in healthy control subjects,however,in patients with asbe- stosis,patients with an uneomfirmed diagnosis for asbestosis and workers exposed to asbestos, the C3 level were significantly lower than in healthy control subjects. The relationship between serum C3 level and the nature of the pneumoconiosis was discussed.更多还原