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特异性玫瑰花试验检测人体抗麻疹细胞免疫功能

Specific E-Rosette Test for Detection of Cell-Mediated Immunity to Measles in Human

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【摘要】 本文报告用“37℃处理麻疹病毒”和“麻疹活病毒”作为抗原,分别对麻疹疫苗1973年初次免疫、1976年或1979年再次免疫及自然麻疹病愈者的外周血淋巴细胞进行特异性玫瑰花试验,以了解受试者特异性细胞免疫功能。结果发现,37℃处理的病毒抗原能增进活性玫瑰花形成,其对活性玫瑰花形成细胞(A-RFC)的平均激活率以1979年再免组最高,1976年再免组和病愈组相似,初免组最低。活病毒抗原能抑制活性玫瑰花的形成。

【Abstract】 A specific E-rosette forming test was carried out to detect cell-mediated immunity in subjects vaccinated with measles vaccine in 1973,revacci- nated in 1976 or in 1979 and in those recovered from natural measles, with living or 37℃-treated measles vaccine-strain as antigens.It was found that the 37℃-treated antigen could enhance lymphocytes in these subjects to form A-RFC.The mean enhancing rate of A-RFC in the 1979 revaccinated group was the highest,in the 1976 revaccinat group it was similar to that of the recovery group,and that of the vaccinated group was the lowest.Living measles antigen could decrease the formation of AREC.

【关键词】 玫瑰花试验麻疹
【Key words】 MEASLES ROSETTE TEST
  • 【文献出处】 浙江医科大学学报 , 编辑部邮箱 ,1984年02期
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