【摘要】 <正> 为深入研究地方性克汀病(以下简称地克病),我们从1981年7月开始,在地克病重病区(患病率为11.04%的集贤大队),利用病区的自然环境和当地生产的粮食、蔬菜和水就地饲养大白鼠,并连续传代,以期复制出接近于人类地克病的动物模型。现更多还原

【Abstract】 The thyroid and brain were Studied in the first generation of rat at 1 ,5 ,10,15,20,30,60 days after they were born of th eir mothers wi th a low iodine diet for 4 months in severe cretinism area.Control groups received a iodine-supPlemented diet. The experimental groups showed obvious thyroid groiter,higher thyroidol ¹²⁵I lptake and reduced brain weight.The ³H-leucine incorporation into brain was uower compared to the control groups.The cerebral and cerebellar histological findings Showed increaced density,reduced sized of neurons and delayed disappearance of cerebellar EGL.This suggestid that the brain development in these animals was markedly retarded.更多还原