【摘要】 本文报道42例卵巢颗粒细胞瘤。临床见腹部包块(81％),腹痛(45％)。发生于右卵巢23例,左卵巢13例,双侧受累者4例。肿物直径最小为5cm,最大为35cm,以5—15cm之间居多(63％)。组织学类型以混合性多见(62％)。据随访观察,凡具三种以上主要临床症状及体征者;瘤细胞核分裂数达(卅)者或具中等以上异型性者,预后均较羞。7例死亡病例中,6例为纯颗粒细胞瘤,提示肿瘤中颗粒细胞成份的多寡,对预后的判断具参考价值。更多还原

【Abstract】 The clinical and pathologic features of 42 cases of granulosa cell tumor of the ovary have been analysed. The youngest patient in this series was 8 years old, the oldest 68, and the average was 47.4. Abdominalmass was palpable in 81％ of this patients, abdominal pain as the common symptom was present in 62％ of our cases. In twenty-three cases the tumors were found in the right ovary and 13 cases in the left; the ratio between the right and eft was 1:0.56, and four (10％) of the cases had bilateral tumors. The size of the neoplasms ranged from 5 to 35 cm diameter, but in most cases it was between 5 and 15. The mixed type (62％) was the dominant histological type. Poor prognosis was proved when the patients presented more than 3 main signs and symptoms (including abdominal mass, abdominal pain and/or distension, ascites and/or weight loss), with mitotic figures 3+or moderate cellular atypica. In fatal cases, six out of 7 cases were pure granulosa cell tumor. The element of the granulosa cell in these tumors was related to prognosis.更多还原