【摘要】 <正> 自从Raab 提出在一定条件下儿茶酚胺(CA)可引起心肌缺血甚至坏死的见解以来,CA 损害心肌的问题受到心脏学研究者们极大注意。已确知,急性心肌梗塞病人CA分泌明显增加,梗塞范围与血、尿CA 水平相平衡。克山病是一种病因明的心肌病,我们测定39例大白鼠心肌组织中儿茶酚胺,为研究克山病与心肌缺血心脏儿茶酚胺含量的变化,为进一步寻找克山病病因提供线索。更多还原

【Abstract】 Catecholamine in heart tissue specimens of 39 rats was determined withan improved fluorometric procedure.Both the stability of fluorophores andthe sensitivity of measurement were markedly higher in comparison with theclassic method.It was seen that the duration of stability was prolonged from5 minutes to 2 hours when ascorbic acid was replaced by mercaptoethanol,and thus the measurement sensitivity was raised up to nanograms.0.3gramof heart tissue is enough for determination by this method.This procedurecan be used for the determination of plasma and urine catecholamine in everybiochemical loboratory.更多还原