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蟾酥针剂治疗小儿再生障碍性贫血25例临床分析

SECRETIO BUFONIS INJECTION IN TREATMENT OF PEDIATRIC APLASTIC ANEMIA

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【作者】 刘家伟; 严淑芳; 吴征远; 刘宜宾; 莫瑜; 陈孝治; 肖轼; 彭六保;

【Author】 Liu Jiawei Yen Shufang Wu Zhenyuan Liu Yibin Mou YuDepartment of Pediatrics, The Second Affiliated Hospital, Hunan Medical CollegeCheng Xiaozhi Xiao Shi Peng LiubaoDepartment of Pharmacy, The Second Affiliated Hospital, Hunan Medical College

【机构】 湖南医学院第二附属医院儿科; 湖南医学院第二附属医院药剂科; 湖南医学院第二附属医院药剂科;

【摘要】 报道用蟾酥针剂治疗小儿再生障碍性贫血 25例的临床分析,与皮质激素联合丙酸睾丸酮治疗的15例进行比较。蟾酥针剂组的疗效显着地优于激素组,且具有显效快速,对本病各种类型均有效,无毒性反应等特点。其作用机制尚待阐明。

【Abstract】 A restrospective analysis of 25 cases of aplastic anemia in children treated with secretio bufonis injection from 1976 to 1984 is presented. Another 15 cases with aplastic anemia in children treated by corticosteroids and testosterone were used for comparison.During hospitalization, in the secretio bufonis treated group 3 cases (12%) were alleviated, 8 cases (32%) obvious improved, 11 cases (44%) improved, and 3 cases (12%) failed to respond, effective rate in total was 88%. While those treated with corticosteriod and testosterone, only 1 case revealed clinical and hemotologic improvement. The follow-up results in patients treated by bufonis injection shewed that 7 cases (28%) were completely relieved with no recurrence in 1-7 years, 6 cases (24%) obviously improved, 5 cases (20%) died, 4 cases out of contact. While those treated with hormone, only 1 case completely rele-ived, 2 cases were chronic an the rest died within 6 months.

  • 【文献出处】 湖南医学院学报 , 编辑部邮箱 ,1984年04期
  • 【被引频次】2
  • 【下载频次】43
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