【摘要】 近两年对38例胃癌进行术前⁶⁰钴照射。本文对30例术前照射标本观察,与同期单纯手术40例对照。 1.本组照射有效率56.6％。根据滝沢氏的X分类,X₁:43％,X₂:40％;X₃:16.6％,照射肿瘤量3,000—4,000rad是适宜的。2.本组未分化癌照射效果最佳,低分化腺癌和管状腺癌次之,乳头状腺癌和粘液腺癌无效。3.间质反应即结缔组织增生和浆、淋巴细胞浸润与对照组比较差异显著（p<0.01）。4.浆膜和粘膜层效果显著。5.胃壁粘膜肌层反应均为可复性的,不影响伤口与吻合口愈合。6.淋巴结转移癌照射有效率62.5％,随照射剂量增加而显著。作者认为胃癌术前照射做为综合治疗措施是可取的。更多还原

【Abstract】 Histologie changes were compared in resected specimens of gastric cancer with （30 patients） and without （40 patients） preoperative ⁶⁰Co irradiation in the same period of time. 1. Marked radiation effect was seen in 56.6％ of the irradiated case, s, 3,000-4,000 rad being considered to be optimal dosage for preoperative therapy. 2. The radiation effect was marked in undifferentiated carcinoma, moderate in poorly differentiated and tubular type, and none in mucous adenocarcinoma and papillary car cinoma. 3. The stromal reaction including fibrous tissue proliferation and lymphocytic infiltration were significantly greater in the irradiated than in unirradiated cases. 4. The radiation effect were marked in sub-serosal and sub-mucosal layers and minimal in muscular layer. 5. The radiation reactions were reversible: they did not interfere with healing of the anastomosis. 6. Response seen in lymphnode metastases （62.5％） increased with increase of dosage. It is concluded that preoperative irradiation of gastric cancer is of definite value.更多还原