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胶乳凝集法测定血清肌红蛋白对克山病诊断的研究

Detection of Serum Myoglobin with Latex Agglutinat ion Test in Patient with Keshan Disease and Its Diagnostic Significance

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【摘要】 <正> 肌红蛋白(Mb)是心肌和骨骼肌的构成成分。当心肌损害时,其中的Mb被释放进入血循环。随之血清中的Mb含量增高。国内外已有不少报告认为测定血清中Mb对急性心肌梗塞早期诊断有价值。克山病是一种原因不明的以心肌损害为主的地方性心肌病。克山病人血中的Mb存在情况以及临床的意义如何,尚未见有报导。1981年我们用聚苯乙烯胶乳凝集试验法检测了52例克山病人血清Mb,

【Abstract】 Detection of serum myoglobin with Latex agglutination test in 52 patientswith Keshan disease was introduced in this paper.In the subacute type, the resultswere positive in all the 30 (100%) cases. In the chronic type, the results werepositive only in 3 (13.5%) of the 22 cases. After death (6 cases), in the 4 cases of subacute type the myocardial pat-hological examinations all showed fresh necrosis. The Latex agglutination test forthe serum myoglobin was positive before death. In the 2 cases of chronic type,there were a lot of old scar, no fresh necrosis was seen, and the detection ofserum myoglobin was negative when the patients were alive. In 14 cases of subacute type and 9 cases of chronic type of Keshan diseasethe results of detection of serum myoglobin with radioimmune assay were consistent with the results of the detection of it with Latex arrlutination test.

  • 【文献出处】 中国地方病学杂志 ,Chinese Journal of Endemiology , 编辑部邮箱 ,1983年02期
  • 【被引频次】1
  • 【下载频次】8
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