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人体免疫球蛋白Gm、Km因子在汉族和维吾尔族人群的分布
The Distribution of Human Immunoglobulin Gm, Km Factors in Han Nationality and Uighurs
【摘要】 调查了790名成都、柳州、上海、长春地区本地汉族人和154名新疆维吾尔族人的Gm、Km因子分布情况。检查了Gm(1,2,3,5,21)因子和Km(ι)因子。结果表明Gm分布的不均一性,从北方向南方Gm1,3;5单倍型频率急剧升高,而同时Gm?和Gm?频率下降。Gm的这种分布格局可能是早先大陆上的两个群体迁移和混杂的结果。在新疆维吾尔族人中发现Gm?单倍型,频率为0.3223,提示存在白种人与黄种人之间的混杂现象。本文调查群体中Km频率呈随机分布。
【Abstract】 A total of 790 unrelated individuals of Han nationality living in Chengdu,Liuzhao,Shanghai,and Changchun regions and 154 Xinjiang Uighurs were typed for Gm and Km factors.All samples were tested for Gm(1,2,3,5,21) and Km(1) factors.The results obtained from Han populations show an evidence of marked heterogeneity in Gm distribution,with a striking north to south clime in haplotype frequencies.The Gm1,3.5 haplotype frequency increases sharply,and there is a concomitant sharp decrease in Gm1;21 and Gm1,2:21 frequencies.This pattern of Gm distributions may be the result of migration and admixture between two previously distinct mainland populations.The discovery that the Xinjiang Uighur population has Gm3:5 haplotype with frequency 0.3223 suggest that there exist admixture phenomenon between Caucasoids and Mongoloids.The distribution of Km1 frequency appears to be random in the presented populations.
- 【文献出处】 遗传学报 ,Acta Genetica Sinica , 编辑部邮箱 ,1983年04期
- 【被引频次】26
- 【下载频次】43