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115例不同肿瘤患者细胞免疫功能的观察

Studies on Cellular Immuno—Responses of 115 Patients with Various Tumours

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【作者】 刘传笃张爱华李仁祯方庆龙崔正言

【Author】 Liu Chuan-du Zhang Ai-hua Li Ren-zheng Fang Qing-long Cui Zhengyan (Shandong Academy of Medical Sciences)

【机构】 山东省医学科学院山东省医学科学院

【摘要】 本文通过ADCC活性和Ea—花环百分率测定,观察了115例不同肿瘤患者的免疫功能状态,对部分病例进行了手术前后、放疗前后免疫功能的动态观察。中早期恶性肿瘤组(包括多种肿瘤)和晚期宫颈癌组的ADCC活性、Ea—花环百分率都显著低于正常组,而良性瘤患者和正常组比较无显著性差异。

【Abstract】 The cellular immuno-responses of 115 patients with various tumors were observed with A D C C activity and Ea-Rosette percentages. A part of them were observed during operation or after irratiation and compared with their original status. A DCC activity and Ea-Rosette percentages showed a significant decline(P<0.05, P<0.01)in early malignant group(of various kinds)and late uterine cancer group and leukaemia patients as compared to that in normal group. Benign tumors group had no statistically significant variation(P>0.05)as compared to that in normal group. Ea-Rosette percentages of malignant tumors group was significantly higher postoperatively than before, and returned to normal level. ADCC activity and Ea-Rosette percentages of the late uterine cancer patients showed a significant decline during radiotherapy process.

  • 【文献出处】 山东医学院学报 , 编辑部邮箱 ,1983年01期
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