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肝细胞表面特化结构的冷冻蚀刻研究

FREEZE-ETCHING STUDY OF MEMBRANE SPECIALIZATION OF HEPATOCYTES

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【作者】 陈细法; 凌治萍; 钟慈声; 俞永富;

【Author】 Chen Xifa;Ling Yiping;Yu Yongfu;Zhong Cisheng Laboratory of Electron Microscopy, Shanghai First Medical College, Shanghai

【机构】 上海第一医学院电镜室; 上海第一医学院电镜室;

【摘要】 本文用冷冻蚀刻技术对小鼠肝细胞表面不同区域特化结构进行观察,详细描述和比较这些区域的微绒毛,紧密连接和缝隙连接的三维结构。根据所见推想成熟肝细胞的紧密连接和缝隙连接都处在不断发育和重建的过程中。同时也观察到在较大的缝隙连接中有空斑存在。

【Abstract】 This paper presents results on different structural specialization of mouse hepatoey-tic membrane by means of freeze-etching replicatechnique. Three-dimensional Structureof microvilli、tight junction and gap junction was recorded and compared. From thesefindings it is suggested that both the tight junction and gap junction are in the processesof continuous proliferation and renewal even in an adult mouse. It was also found thatthere are plaques without closely packed polygonal array of particles in the center ofthe larger gap junction.

  • 【文献出处】 电子显微学报 ,Journal of Chinese Electron Microscopy Society , 编辑部邮箱 ,1983年03期
  • 【被引频次】2
  • 【下载频次】38
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