【摘要】 用吡喹酮对237例华支睾吸虫病患者进行治疗观察,并以六氯对二甲苯治疗40例作为对比。治后4个月复查表明,吡喹酮总剂量120毫克/公斤组的粪虫卵阴转率达97.1％,显著高于六氯对二甲苯组。治后患者症状及体征均有所改善。药物反应以吡喹酮治疗组轻。与六氯对二甲苯相比,吡喹酮疗程短,反应轻,疗效亦佳,是值得推荐的新药。更多还原

【Abstract】 237 cases of Clonorchis sinensis infection were treated with pyquiton and, for comparison, 40 cases with hexa-chloro-p -xylol ( Hetol ) . Stool egg negative conversion rates four months after pyquiton treatment ( with total doses of 60 and 75mg/kg ) were similar to that of hexa chloro-p-xylol. In group with total dose of 120 mg/kg, the egg negative conversion rate was 97.1%, being much better than that of other groups. The average egg reduction rates in all groups were above 98% 4 months after treatment. After pyquiton or hexa-chloro-p-xylol treatment in some of the patients symptoms disappeared and signs improved, Side effects of pyquiton were slight. Authors suggested that pyquiton was a drug of choice with higher efficacy and shorter course.更多还原