【摘要】 作者报道用吡喹酮治疗55例急性日本血吸虫病患者的疗效。除 1例外,均退热至正常,总的粪便毛蚴孵化阴转率为90.4％。其余7例用硝硫氰胺治疗者退热较慢,亦能使粪便毛蚴孵化阴转,但副作用较大。更多还原

【Abstract】 62 cases of acute schistosomiasis japonica were treated with pyquiton ( praziquantel ) or nithiocyamine ( amoscanate ) .In all 55 cases treated with pyquiton ( total dose 60-140mg/kg, 2-6 day regime ) , fever subsided about 10 days after treatment with only one exception. Stool hatching became negative in 47 out of 52 cases (90.4%) . In 7 cases treated with nithiocyamine ( total dose 10-12mg/kg, 6-day regime), fever subsided slowly ( about 15 days) and side effects were more severe. One case after nithiocyamine therapy showed a positive hatching test. Authors suggest that pyquiton is a drug of choice with high efficacy and low toxicity and worth recommendation.更多还原