【摘要】 <正> 抑素(Chalone)是一类细胞内重要的增殖抑制因子,目前已被分离出有10多种,其中粒细胞抑素研究得较为广泛。关于抑素抑制正常及癌细胞的作用,国外已有介绍。国内尚未见报导。本文主要研究了粒细胞抑素的制备方法及其体外活性测定,该活性物质生物学特性及组分初步的分析。更多还原

【Abstract】 This paper reports the separation and demonstration in vitro of the specific granulocyte chalone DNA duplication in murine bone marrow is effected significantly by means of granulocyte chalone We observed that the granulocyte chalone inhibits 38.5% of ~3H TdR incorparation into murine bone marrow cell in vitro at a concentration of 400 ug/cc, and the degree of inhibition is dependent of chalone’s concentration. The biological activity of ehalone has cell specificity but without species specificity.更多还原