【摘要】 本文报告用正常人皮疱试验,观察到针麻病人伤口血致痛反应与针麻效果有关,伤口血致痛反应的特征与激肽及5-羟色胺相似,发现针麻效果好的病人形成激肽能力降低,破坏激肽能力增强,血中游离5-羟色胺含量下降,表明针麻病人血中激肽体系和5-羟色胺含量变化与针麻效果密切相关。更多还原

【Abstract】 This paper reports the changes of blood kinin system and serotonin in patients during subtotal gastrectomy and abdominal hysterectomy under acupuncture anesthesia.Blood from traumatic areas in patients with poor acupuncture anesthetic effects caused sever pain when dropped on the denuded skin of forearm, made by cantharidin blister, but blood from traumatic areas in effective cases not.Characteristics of painful response caused by wound blood were similar to those caused by bradykinin and serotonin. So changes in plasma kinin system and serotonin were studied. Results indicated that acupuncture may regulate the plasma kinin system by decreasing of kallidin level , stabilizing of kininogen and particularly increasing of kininase activity. As aresult, the bradykinin concentration in plasma was reduced.Serotonin was determined in patients during hysterectomy. It was shown that the content of serotonin was decreased in cases with excellent effects but increased in those with poor effects.更多还原