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鼻咽癌漏诊或滞诊病例的病理分析

A Pathologcial Case Analysis of Failed or Delayed Diagnoses of Nasopharyngeal Carcinoma (NPC)

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【作者】 宗永生; 姚庆云; 何深云;

【Author】 Tsung Yung-sheng Yao Qing-yun He Shen-yun (Cancer Research Institute, Zhong Shan Medical College. Department of Pathology, People’s Hospital of Zhong Shan County)

【机构】 中山医学院肿瘤研究所病理、免疫室; 中山县人民医院病理室;

【摘要】 <正>临床上怀疑为鼻咽癌的患者,只要取材恰当,标本固定良好,切片薄,染色清晰,不难作出正确的病理诊断。但在实际工作中,仍有极少数病例,虽经活检,由于各种原因而发生漏诊及滞疑者,需要再次作病理检查,方能确诊。这样不仅增加了病人的痛苦,而且延误了确诊时间,影响患者的治疗。为了进一步提高活检诊断的准确率,特将我们所收集到的鼻咽癌病例中,病理检查发生漏诊或滞疑者共39例,作一复习,总结经验教训,供同道参考。

【Abstract】 The authors reviewed all the pathologic slides of NPC patients from whom more than two biopsies had been taken before treatment in a high risk area, Zhong Shan County during the last nine years. It was found that there were 9 cases, formerly reported as "No carcinoma was found" and 30 cases, as "May be carcinoma, please take biopsy again" on the first biopsy slides should be suspected to be NPC by reading these slides again at the time of reexamination. There were 1,092 cases of NPC confirmed pathologically altogether, therefore the failured diagnotic rate was 0.82% and delayed definitev diagnosis was 2.75%.The authors summed up the causes of mistakes as follows: (1) The biopsy slide was not well-done and artificial shrinkage was present. (2) Early carci-nomatous lesions were neglected. (3) Due attention was not paid to the fusiform carcinoma cells. (4) No notice was taken of undifferentiated cell carcinoma. (5) Detailed search for scattered vesicle-nuclear carcinoma cells was not done (8) The examiner was not safficiently experienced in surgical pathology.

  • 【文献出处】 中山医学院学报 , 编辑部邮箱 ,1980年02期
  • 【被引频次】1
  • 【下载频次】16
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