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日本血吸虫卵卵壳的超微结构

SCANNING AND TRANSMISSION ELECTRON MICROSCOPY OF SCHISTOSOMA JAPONICUM EGG SHELL

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【作者】 何毅勋; 龚祖埙; 马金鑫;

【Author】 He Yixun Gong Zuxun Ma Jinxin Institute of Parasitic Diseases, Chinese Academy of Medical Sciences. Institute of Biochemistry, Academia Sinica. Institute of Entomology, Academia Sinica.

【机构】 中国医学科学院寄生虫病研究所; 中国科学院上海生物化学研究所; 中国科学院上海昆虫研究所 上海;

【摘要】 本文报告了应用扫描电镜及透射电镜研究日本血吸虫卵卵壳超微结构的结果。卵壳是由薄的电子密度非常致密的连续性的内层和厚的中等电子致密的均匀外层所构成的。在卵壳表面布满平均为0.06×0.02微米的微棘和平均为0.18×0.06微米的微棘样突起,每平方微米卵壳表面的微棘数目约600根。对于卵壳的微棘及微棘样突起的生理作用及其在发病机理中的意义进行了讨论。

【Abstract】 In this paper ultrastructural observations on the egg shell of Schistosoma japonicum are presented. These observations were made in order to understand the role played by the egg shell in the pathogenesis and in the circumoval precipitation test.It is shown that S. japonicum eggs have a rudimentary lateral spine (Figs. 1, 2) . The surface of the egg shell of S. japonicum is quite rough as visualized with SEM ( Figs. 3, 4 ) and it is of extremely complicated structure as visualized with TEM. The thickness of the egg shell of S. japonicum is about 0.4μ, and the shell itself is composed of a thin, very dense, apparently continuous inner layer and a thick, moderately dense outer layer ( Figs. 5, 6 ) . The outer surface of the egg shell is covered with numerous brush-like microspicules that average 0.06μ in length and 0.02μ in diameter at the base. There are about 600 microspicules in each square micron of the egg shell surface. Some microspicule-like projections, about 0.18×0.06μ on the average, may also be found at intervals of certain distance (Figs. 6, 7 ) . The top of the projection is easily broken and drops off. If debris of the projections deposit in vessels or tissues such as glomeruli of the kidney in host, they might act as one of schistosomal antigens. Whether debris of the projections are involved in the immunology or in the pathogenesis of schistosomiasis is worthy of notice.

  • 【文献出处】 中国医学科学院学报 ,Acta Academiae Medicinae Sinicae , 编辑部邮箱 ,1979年02期
  • 【被引频次】16
  • 【下载频次】56
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