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磷酸盐緩冲液,血清及全血对酒石酸銻鉀刺激性的影响以及酒石酸銻鉀与酒石酸銻鈉刺激性的比較
THE LOCAL IRRITATING ACTION OF ANTIMONY POTASSIUM TARTRATE AND ITS SODIUM ANALOGUE
【摘要】 <正> 酒石酸銻鉀(以下筒称銻鉀)由于刺激性大,只能靜脉注射,不便于大規模应用,在未发現較銻鉀更好的藥物以前,設法减低銻鉀的刺激性,改变其給藥途徑,仍是值得研究的問題。
【Abstract】 Experimenting with guinea pigs for intradermal injection and rabbits for intramuscular injection, the effect of phosphate buffer solution (0.5M,PH 7.2), whole blood and serum on the irritating action of tartar emetic was studied, and the intensity of the irritating action of antimony potassium tartrate and its sodium analogue compared.It was found that:(1). the phosphate buffer solution was without effect, the whole blood increased the irritating action of tartar emetic; while serum decreased it duriug intradermal injection.(2). no difference was observed in the intensity between the irritating action of antimony potassium tartrate and that of antimony sodium tartrate.
- 【文献出处】 武汉医学院学报 , 编辑部邮箱 ,1957年04期
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