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在高溫作业下血液中丙酮酸,乳酸和二氧化碳結合力的变动,以及相应的丙酮酸和乳酸的排出情况

STUDIES ON THE VARIATIONS OF PYRUV1C ACID, LACTIC ACID AND CARBON DIOXIDE COMBINING POWER IN THE BLOOD,AND THE EXCRETION OF PYRUVIC ACID AND LACTIC ACID IN THE URINE AND THE SWEAT OF MEN WORKING IN HIGH TEMPERTURE ENVIROMENT

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【作者】 張華徵; 孟天真; 孫家寿; 张国霖; 趙深士; 王巽義;

【Author】 Chang Hwa-Cheng, Meng Tien-Cheng, Sun Chia-Shou, Chang Kou-LingChao Shen-Shih, and Wang Sun-I Department of Biochemistry, Wuhan Medical College, Hankow, China

【机构】 武汉医学院生物化学教研组; 武汉医学院生物化学教研组;

【摘要】 <正> 体力劳动,对于血液中丙酮酸,乳酸和二氧化碳結合力有显著的影响,早为吾人所素知: Haruhisa Yoshikawa等(1949)报告小腿弯曲运动90—180秒鐘后血中丙酮酸及乳酸的水平皆上升,其中丙酮酸的增加数值較乳酸为小,其速度也較为緩慢。若此运动延續夕則血中丙酮酸及乳酸水平亦将繼續上升,并且也需要較长时間的休息才能使二者的水平恢复正常。O G.A.Goldsmith等(1948)

【Abstract】 Ⅰ .Blood determinations were done in 2 groups of workmen,one group of 24 men working under high temperature condition, and the other group of 41 men working under radiation heat. These two groups are further divided into several sub-groups according to the time at which the study was done.( 1 )In the radiation heat group the average carbon dioxide combining power of the blood for the sub-group studied before work was 53. 2c.c.%; 2 hours after work, 52. 1 c.c. % ; 6 hours after work, 52. 6 c.c. %; 8 hours after work, 53. 1 c. c. 96; 1 hour after rest, 59. 4 c.c. %. In the high temperature group the average for the sub-group before work was 55. Oc.c.% ; 6 hours after work,52. 8c.c.%; 8 hours after work,55. 8c.c.%.( 2 )In the radiation heat group the average pyruvic acid for the sub-group studied before work was 1 . 74 mgm %; 2 hours after work, 1.80 mgm %; 6 hoars after work, 1.55 mgm %; 8 hours after work, 1 .27mgm %; 1 hour after rest, 1 . 20 mgm %. In. the high temperature group the average for the sub-group before work was 2.01 mgm % ;6 hours after work, 1 . 28 mgm %; 8 hours after work, 1 .08 mgm %.(3 )In the radiation heat group the average lactic acid for the sub-group studied before work was 10. 7 mgm %; 2 hours after work, 13.3 mgm %; 8 hours after work, 12.7 mgm %;, 1 hoar after rest, 15. 2 mgm%. In the high temperature group the average for sub-group before work was 16. 4 mgm%; 6 hours after work, 20. 3 mgm %; 8 hours after work, 11. 7 mgm %. ,Ⅱ.The urinary excretion of lactic acid in 15 men of the radiation heat group and of pyruvic acid in 8 men of the same group were determeined. The average concentration of the lactic acid in the urine excreted before work was 7. 60 ±1.03 mgm %; after 4 hours, of work, 5 .86 ± 0.54 mgm %;after 8hours oY work, 6 .56 ± 0.64 mgm %; in the 24 hours urine sample, 5 .94 ± 0.70 mgm %; The average concentrtion of lactic acid in the urine was 6.56 ±0.42. The average concentration of pyruvic acid in the urine excreted before work was 2 .47± 0.53 mgm %5after 4hours of work, 2 .49 ± 0.76 mgm%;after8 hours of work, 2.47±0.75 mgm %; and in 24 hours urine sample, 2. 57± 0.61 mgm %;.The average concentration of pyruvic acid in urine was 2 .57 ± 0.31 mgm%.Ⅲ.The concentration of lactic acid in the sweat in 17 men of the radiation heat group and pyruvic acid in the sweat’ in 12 men of the same group were determined. The sweat collected individually during work at three different intervals. The average concentration of the lactic acid in the sweat for the first collection was 170 ± 10.7 mgm; for the second collection, 154.4± 13.4 mgm %;for the third collection 156± 8.4 mgm %.The average concentration of the lactic acid in the sweat was 158.4 ±6.4mgm%. The average concentration of the pyruvic acid in the sweat for the first collection was 7.5 ± 1.06 mgm %; for the second collection, 6 .00 ± 0.71 mgm %; for the third collection, 6 .38 ± 0.85 mgm. The average concentration of the pyruvic acid in the sweat was 6.6 ±0.53 mgm %.Ⅳ.According to the above results, the correlations among carbon dioxide combining power, lactic acid, and pyruvic acid in blood, urine and sweat, and their importance in mainta ning acid-base balance were discussed.

  • 【文献出处】 武汉医学院学报 , 编辑部邮箱 ,1957年03期
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