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药物性皮炎的临床研究 Ⅳ.血吸虫病短程疗法中锑剂皮炎的发病情况和发生机制的研究
Clinical Studies on Dermatitis Medicamentosa:Ⅳ.A Clinical and Pathogenetic Study of Antimony Dermatitis during the Treatment of Schistosomiasis
【摘要】 <正> 锑剂在医药中的应用是相当广泛的,但其所产生的皮肤炎性反应,直到现在为止国际文献中的报导,并不常见。由于血吸虫病在我国流行较广,为了缩短治疗时间,自1956年起,多数采取短程疗法,即将过去的30天和20天长程疗法缩短到7天、5天以至3天。随着疗程的缩短,锑剂皮炎病例也逐渐增加。通过病例的
【Abstract】 Since the adoptation of shorter courses of antimony therapy,a new type of antimony dermatitis was frequently observed.Its incidence was about 30—40% or even higher.Its incubation period was 2—3 days.The skin lesions were localized over the face and back of the hands and fingers in the form of pinpoint to pinhead sized reddish papules and papulo-vesicles on erythematous bases accompanied with mild it- ching.Its course was self-limited,being disap- peared spontaneously in 3—5 days even without treatment.Antimony therapy could be continued as usual without interference in the treatment of schistosomiasis,unless more severe reactions made their appearance. Owing to the higher dosage of antimony, high incidence,short incubation period and non- interference of continuation of the same therapy, the condition was considered to be toxic rather than allergic in nature,althoush clinically it was very mild and selflimited.
- 【文献出处】 上海第一医学院学报 , 编辑部邮箱 ,1965年02期
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