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黏液水肿性苔藓伴发轻链免疫球蛋白病1例

A Case of Lichen Myxedematosus with Light Ligand Gammopathy

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【作者】 卢晓红许丛丛杜文辉李卉林达王培光

【Author】 LU Xiaohong;XU Congcong;DU Wenhui;LI Hui;LIN Da;WANG Peiguang;Department of Dermatology and Venerology,the First Affiliated Hospital of Anhui Medical University;

【机构】 安徽医科大学第一附属医院皮肤性病科

【摘要】 患者男,52岁,躯干四肢泛发性皮损4个月余。体检:躯干、四肢弥漫密集分布肤色或淡红色扁平丘疹。皮损组织病理示:真皮浅层黏液样变性,真皮胶原纤维增生伴玻璃样变;阿新兰染色阳性。免疫固定电泳:Ig G(+),轻链λ(+)。诊断为黏液水肿性苔藓伴发Ig G-λ轻链免疫球蛋白病。

【Abstract】 A 52-year-old male presented with widespread rashes in his trunk and limbs for more than 4 months. Physical examination showed diffuse,grouped,skin-colored or reddish flat papules. The lesional histology revealed mucin-like degeneration in the superficial dermis,proliferation and hyaline degeneration of dermal collagen,accompanied by positive alcian blue staining. Immunofixation electrophoresis showed positive immunoglobulin G-λ light chain. Therefore,the patient was diagnosed as lichen myxedematosus associated with Ig G-λ light chain gammopathy.

  • 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,2018年08期
  • 【分类号】R758.6
  • 【被引频次】3
  • 【下载频次】111
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