【摘要】 目的探讨降钙素原(PCT)在判断开颅术后合并感染病原菌种类中的价值。方法回顾分析近五年我院神经外科103例开颅术后合并感染患者,根据合并感染的病原学诊断和临床诊断标准分为革兰阴性菌组、革兰阳性菌组和非细菌性组,并分析各组病原菌与PCT水平的相关性。结果开颅术后合并感染患者的PCT浓度:革兰阴性菌组>革兰阳性菌组>非细菌性组,而CRP水平在三组间差异无统计学意义。结论开颅术后合并感染病原菌种类与PCT水平有一定相关性,监测PCT水平对辅助临床判断开颅术后合并感染病原菌种类有临床应用价值。更多还原

【Abstract】 Objective To evaluate the value of Procalcitonin( PCT) in identifying the species of pathogens in postcraniotomy intracranial infection. Methods Retrospective analysis was performed on 103 cases of post-craniotomy intracranial infections in the neurosurgery department of our hospital in recent 5 years. Based on the etiological diagnosis and clinical criteria for diagnosis of intracranial infection,these cases were divided into gram-negative bacteria group,gram-positive bacteria group and non bacteria groups,and the correlation between each group of pathogens and PCT level were analyzed. Results The PCT level of patients with post-craniotomy intracranial infection was the highest in Gram negative bacteria group,followed by gram positive bacteria group,and lowest in non bacteria group,but there was no statistically significant difference in CRP levels between the three groups. Conclusion The pathogen species in post-Craniotomy intracranial infection has some correlation with PCT levels; monitoring PCT levels may be of clinical value for determining the species of pathogens in post-craniotomy intracranial infection.更多还原