【摘要】 目的探讨我国膀胱癌死亡现状及流行趋势。方法收集整理全国肿瘤登记中心1998～2008年登记的膀胱癌数据,包括膀胱癌死亡率、0～74岁累积死亡率、死亡构成及年龄别死亡率。分别按性别及城乡差异进行统计,分析中国男性与女性、城市与农村膀胱癌的死亡现状和趋势。死亡率的年均变化百分比(APC)通过对死亡率进行对数转换的线性回归分析计算。采用Joinpoint模型回归分析死亡率流行趋势。结果 2008年,全国肿瘤登记地区膀胱癌的死亡率为2.63/105,0～74岁中国人口膀胱癌累积死亡率为0.12%,占中国恶性肿瘤死亡构成的1.42%。中国男性膀胱癌死亡率(3.89/105)是女性(1.34/105)的2.9倍。中国城市人口膀胱癌死亡率(2.86/105)是农村人口(1.76/105)的1.6倍。1998～2003年间膀胱癌死亡率呈波动下降趋势,2003～2008年呈逐年增长趋势。2008年中国膀胱癌年龄别死亡率与1998年相比,高龄组患者的死亡率有所降低。结论中国属于膀胱癌死亡水平较低的国家之一,1998～2008年的11年间中国膀胱癌死亡率相对稳定,但近5年间的死亡率呈现逐年增长趋势。人口老龄化可能是中国膀胱癌死亡率增长的原因。更多还原

【Abstract】 Objective To investigate the status quo and trends of bladder cancer mortality in China.Methods Bladder cancer data between 1998 and 2008 from the National Cancer Registration Center were collected,including the mortality of bladder cancer,the cumulative death rate of people aged 0-74,the death cause and the age-specific mortality.The mortality differences between male and female,urban and rural areas were analyzed.The annual percentage changes(APCs) in mortality were calculated by linear regression analysis on the logarithmic transformation.The time trends of bladder cancer mortality in patients with bladder cancer in China were analyzed with Joinpoint regression model.Results In 2008,the Chinese mortality of bladder cancer was 2.63/105,the cumulative morality of people aged 0-74 was 0.12%,accounting for 1.42% of deaths caused by malignant tumors.The mortality of male(3.89/105) was 2.9 times of that of female(1.34/105).In rural areas,the mortality rate was 2.86/105,which was 1.6 times of that in urban areas(1.76/105).During 1988-2003,the mortality showed a fluctuating downward trend.During 2003-2008,the mortality rate was rising.In 2008,the mortality of elderly patients declined in age-specific morality compared with that in 1988.Conclusions The mortality of bladder cancer in China is moderate.During the past 11 years,the morality has showed a stable tendency,but in the recent 5 years,the morality has been rising.The aging of the population may be the main reason for the increase in mortality in patients with bladder cancer in China.更多还原