【摘要】 目的探讨不伴有弱视的恒定性外斜视儿童的多导视觉诱发电位（ｖｉｓｕａｌｅｖｏｋｅｄｐｏｔｅｎ－ｔｉａｌｓ，ＶＥＰｓ）的临床意义及外斜视的发病机理。方法采用１４个盘状作用电极行全视野及半视野棋盘格翻转刺激，记录正常对照组与不伴有弱视的恒定性外斜组儿童的视觉诱发电位。结果斜视组全视野刺激所记录的双眼与单眼ＶＥＰｓ潜伏期（ＬＰ１）、振幅（ＡＮ１Ｐ１）比较，差异无显著性（Ｐ＞０．０５），此结果与正常对照组不同；斜视组主眼和非主眼ＬＰ１较正常对照组延长（Ｐ＜０．０１），斜视组非主眼ＡＮ１Ｐ１较正常对照组下降（Ｐ＜０．０１）；斜视组鼻、颞侧视网膜ＬＰ１、ＡＮ１Ｐ１比较，差异无显著性（Ｐ＞０．０５）。结论ＶＥＰｓ检测可为恒定性外斜视者的双眼视功能异常提供客观依据；恒定性外斜视者视力虽正常但ＶＥＰｓ并非正常，提示有初级视皮层功能障碍存在；不伴有弱视的恒定性外斜视者在单眼半视野刺激条件下，无颞侧视网膜抑制现象。更多还原

【Abstract】 Objective To investigate the clinical significance of multichannel visual evoked potentials (VEPs) in constant exotropic children without amblyopia and the mechanism of exotropia. Methods With 14 active cup electrodes, and full and half field stimulation, the checkerboard pattern was reversed and the VEPs were recorded in control and experimental groups. Results With full field stimulation, the latent period 1 (LP1) of binocular VEPs was not longer and the amplitude N1P1 (AN1P1) not higher respectively than those of monocular VEPs in experimental group. These properties were different from those of control group. The AN1P1 of nondominant eye was decreased, and the LP1 of dominant and nondominant eye was longer in experimental group than that of the control group. There were no significant differences in comparing LP1 and AN1P1 between nasalretina and temporalretina of experimental group. Conclusions VEPs can provide a scientific basis for abnormal binocular vision in constant exotropia. Although the visual acuity of constant exotropic children is normal, their VEPs are abnormal. Therefore, there might be dysfunction in primary visual cortex. With half field stimulation, there is no suppression of temporalretina in monocular VEPs of constant exotropic children.更多还原