节点文献
基于基因工程的机械产品设计理论与技术研究
Research on Theory and Technology of Mechanical Product Design Based on Genetic Engineering
【作者】 陈洪武;
【导师】 黄克正;
【作者基本信息】 山东大学 , 机械设计及理论, 2005, 博士
【摘要】 本文首先提出了本课题研究的背景和意义,探索产品基因工程设计理论,力争实现产品设计的自动化,支持产品创新设计,介绍了生物基因工程以及在非生物领域的应用,综述了概念设计研究的现状和有待解决的问题。 在基础理论方面,从创新设计的角度出发,依据分解重构理论和生物基因工程,提出了机械产品基因工程设计理论。通过与生物生长过程的系统比较,将产品比作生物个体,提出产品基因新概念,揭示了产品基因的控制机理,包括产品基因的“转录”、“翻译”、“逆转录”等表达机制。为支持产品基因工程设计理论,还提出了利用功能表面集对应需求功能基因的功能表面理论、解决功能—结构映射问题的广义定位原理、以及用于产品基因表达的生长型设计方法。 在技术研究方面,提出了支持产品基因工程的关键技术,包括产品基因获取技术、产品基因扩增技术、产品基因重组技术以及产品基因表达技术。在产品基因模型的基础上,从现有产品中获得产品基因,构建产品基因文库,用于获得目的基因。产品基因扩增是指产品基因相关信息的扩展、增广的过程,是产品信息的扩增。产品基因的重组,首先需要得到分离出不良基因的载体基因,以及在产品基因文库中查找到优良的目的基因,然后依据产品基因重组规则实施重组,最后对重组的产品基因进行评价,并转移到产品基因的生长系统中。产品基因的表达技术,是将产品遗传信息体现在产品的结构设计中,从而决定产品的功能特性和结构特点,本文将产品基因的表达过程分为产品基因的转录过程和翻译过程。 在系统开发和应用方面,研制开发了支持产品基因工程设计理论的工具系统PGE-DARFAD,它是基于DARFAD系统,扩展了产品基因获取、产品基因扩增、产品基因库构建、产品基因重组以及产品基因表达等功能模块。本文以虎钳夹具为设计实例,运用产品基因工程设计原理及其关键技术,分析了三种虎钳夹具的设计过程及优缺点,总结出较优的设计方案,分别得到了其概念结构和实体结构,以说明产品基因工程工具系统的设计效果。
【Abstract】 This paper firstly puts forward background and significance of research, that is, tries to explore new design theory by use of biological genetic engineering for reference to support innovation design and design automation, and improve CACD power. Secondly it sums up the current research of biological genetic engineering and application in non-biological field, introduces the state-of-the-art of domestic and international research in CACD, and furthermore proposes the problems remained in conceptual design.From the angle of design innovation, the paper has established the design theory based on PGE according to R&D (Decomposition and Reconstitution) theory and biological genetic engineering principle. The following similar relations can be proposed: Gene in biology —>Product Gene(PG) and Organism —>Product after a systematic study of the similarities between the innovation design and biological genetic engineering. Moreover, we also put forward PG’s working mechanisms of "replication", "transcription", "translation" and "reverse transcription". Study on mechanical product design automation theory and development practice have resulted in some design principles such as "Functional Surface" principle, "Generalized Locating" principle and "Growth Design" principle based on PGs. Functional Surface principle makes use of Functional Surface as a carrier of the information including geometrical and functional feature to solve the process of function-structure mapping relationship. "Generalized Locating" principle is the core of solving the structure question, and "Growth Design" based on PGs is the matrix in which PGs express. These principles are the important parts in design theory based on PGE.In technical research, the paper has put forward four kinds of technologies based on PGE theory, such as PGs obtainment, PGs amplification, PGs recombination and PGs expression. PGs obtainment is the process of extractingthe PGs from existing product. The paper also introduces the database technologies to structure gene library of PGs so that target gene can be indexed from the gene library according to requirements to recombine target gene and carrier gene. PGs amplification is the expansion of PGs information related. PGs recombination refers to the design process: firstly get the carrier PG through isolating bad PGs, find out target PGs indexing PGs Base, and finally recombine carrier PG and target PGs according to the PGs recombination rule. PGs expression is to reflect the genetic information of products in process of structural design. Thus PGs can determine function and structure characteristic of products. Accordingly PGs are "transcribed" by design scheme into conceptual architecture and that conceptual construction is then "translated" by detail design into solid.Previous theoretical study and corresponding technologies have resulted in the establishment of tool software system PGE-DARFAD, which is based on product growth design platform DARFAD system. PGE-DARFAD has expanded such function module as PGs obtainment, PGs base construction, PGs amplification, PGs recombination and PGs expression, etc. Finally, we introduce an example of vise fixture based on PGE, analyze and summarize three kinds scheme, in order to illustrate the effect of system.
【Key words】 Genetic Engineering; Conceptual Design; Product Gene; Functional Surface;