【作者】 吴童；

【导师】 常存库；

【作者基本信息】 黑龙江中医药大学 ， 中医医史文献， 2005， 博士

【摘要】 本文通过文献研究与现代统计学分析相结合的方法,探求消渴病的演变轨迹及证治规律,期望能够为有效防治消渴病(糖尿病)提供更多借鉴和新的思路。首先,运用文献学的方法,收集整理古代文献,从历史发展的角度,对历代医家关于消渴病的论述进行了全面总结和回顾。系统分析消渴病的病名沿革、病因、病机、辨证、治则、方药等诸多方面,力求从整体上认识消渴病辨证论治的发展规律,为今后的研究奠定文献基础。其次,将古代治疗消渴病方药建立数据库,利用SPSS统计软件对其进行频数、因子、聚类等数理统计,从方药的频数和剂量二个角度,分析研究唐宋、金元、明代、清代各个历史时期和中医学整体上对消渴病的证治规律和特点。通过双频关联法分析得出补虚药、清热药是治疗消渴病的主要两类药物这一重要结论。通过因子分析得出热盛津亏、气阴两伤,与水湿内停等复杂的病机变化以及通过聚类分析得出相应的方药配伍关系。第三,通过对消渴病与糖尿病的关系及文化层面的解读,以及对消渴病的三消论治思想和消渴病本虚标实属性的认识,有助于全面客观地分析评估中医治疗消渴病(糖尿病)的优势和缺陷。第四,总结出历代各时期治疗消渴病方剂中的主药26味,这些药物最能体现当时消渴病证候群的分型归属及治法。在这26味药物中,补虚药9味,清热药7味,占上述药物的近2/3。提示热盛伤阴,气血两虚应是消渴病历代总的证候群的分型归属。从归经分类看,三焦脏腑归经药物大致均等,显示着三焦分治是古代中医治疗消渴病的总体认识。更多还原

【Abstract】 This thesis probed the development of diabetes of TCM and its syndrome-treatment and prescription-drugs through combining documentary study with modern statistic method, and more consulting and new ideas effectively preventing and treating diabetes of TCM were wished to be offered.Firstly, using documentary method to gather and sorting out ancient diabetic document of TCM, and summarizing and reviewing generally diabetic thesis of doctors in every dynasty from history developing angle, and analyzing systematically its name history, disease cause, pathogenesis, differentiation of symptoms and signs, principle of treatment, prescription-drugs and so on. Trying to find the developing regular of treating diabetes of TCM in accordance with differentiation of symptoms and signs, which was basic research of documentary study in future.Secondly, to establish the database of ancient prescription treating diabetes of TCM, and using the software of SPSS to deal with frequency, factor analysis and clustering analysis, and analyzing the regulation and characteristics of syndrome-treatment of diabetes of TCM both in Tang-song, Jin-yuan, Ming and Qing Dynasty and on concept of wholism of TCM from frequency and dosage. An important conclusion was made that tonifying drug and heat-clearing drug are two main kinds of drugs treating diabetes of TCM with bispectrum relevance method, and it was also concluded that pathogenesis change of diabetes of TCM were deficiency of fluid duo to exuberant fire, deficiency of qi and yin and water-dampness stagnating in body through factor analysis, and更多还原