Response surface methodology was used to optimize the submerged fermentation media of cellulase production by Trichoderma reeseiWX-112. In the initial optimization step, the path of steepest ascent was used to approach the optimal region of the cellulase production. The response surface experiment was subsequently designed according to the result of steepest ascent. The optimal regression equation model which expressed the relationship between the filter paper activity(FPA) and soy bean cake powder, wheat b...
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