Objective To study the relationship between hepatic fibrosis and osteoporosis, and to observe the effects of Danshen on preventing bone loss Methods Forty PCR mice were randomly divided into 4 groups. Mice in the control group were treated by daily oral gavage with vehicle. Mice in other three groups were given subcutaneous injection of 40% CCl_4 10ml·kg~ -1 and treated by either daily oral gavage with vehicle, or colchicine, or Danshen for 42 d. The liver injury indexes were measured and the mineral elemen...