Objective:To explore the electrocardiogram changes of myocardial ischemia(30 min) and reperfusion(120 min) in rats. Methods:We selected 16 SD rats to set up models of myocardial ischemia and reperfusion,and observed the changes of P complex,QRS complex,T wave,S-T segment and the occurrence of arrhythmia in electrocardiogram of lead Ⅱ. Results: ①12 models were useful.② R waves of the 12 models rose transitorily and abnormally during the occlusion of the left coronary artery;new q waves appeared or original q...
【基金】
江苏省“六大人才高峰重点课题”基金资助项目(批准号:2005A6)
【更新日期】
2006-08-31
【分类号】
R-332
【正文快照】
0引言大鼠心肌缺血-再灌注模型是模拟人类心肌梗死及再通治疗,研究缺血预适应机制,评价抗心肌缺血及心律失常药物疗效常用的动物模型,目前已成为研究的热点问题,但对大鼠心肌缺血-再灌注过程中心电图改变研究不多。本研究分析了16只大鼠心肌缺血30 m in、再灌注120 m in的心电?