Progress of the research on production of plant drug secondary metabolites by cell culture is discussed in this paper.Plant secondary metabolism is the main source of many fine drugs.There are many methods used in cell culture to improve the secondary metabolite production,such as:screen cell lines,optimize the culture conditions,immovable cell culture,use elicitor,hairy-root culture.Engineering of plant secondary metabolism is feasible nowadays,but it requires knowledge of the biosynthetic pathways involve...