Purpose To investigate the diagnostic significance of hepatocyte growth factor(HGF), interleukin 6(IL 6) in early experimental hepatocellular carcinomas. Methods The serum levels of HGF, IL-6 were measured by ELISA. The expression of HGF, IL 6 in the liver tissues of rat early experimental hepatocellular carcinomas and human hepatoma cell lines were studied by immunohistochemistry, immunocytochemistry and electron microscopic immunocytochemistry. Results HGF, IL 6 were expressed in the cytoplasm o...